He has written 19 peer-reviewed journal articles and contributor to two books on feline anesthesia and analgesia with an additional in preparation. His most notable research focuses on the effects of aging on opioid analgesia, opioid-opioid  interactions (ie hydromorphone and butorphanol combinations) and their effects on thermal antinociception, ultra-low dose dexmedetomidine infusions in cats, and the utility of acupuncture and pharmacopuncture in small animal practice. He has also published several impactful reviews on the present and future of opioid analgesics and on the lack of analgesic use (oligoanalgesia) in small animal practice. Dr. Simon is a national and international lecturer and has presented at the International Conference on Opioids at Harvard University, World Small Animal Veterinary Association Conference in Colombia, World Congress of Veterinary Anesthesia in Italy, and Congreso Veterinario in Mexico. As an invited speaker, Dr. Simon hopes to continue his path of spreading knowledge about pain management to the veterinary profession and general public.